Encyclopedia of AIDS, Hope T.J., Richman D.D., Stevenson M., 2018

Encyclopedia of AIDS, Hope T.J., Richman D.D., Stevenson M., 2018.
     
   The AIDS Encyclopedia represents an AIDS “Wikipedia.” It is a dynamic, online reference work that can be updated by researchers and by editors that will be able to keep pace with developments in the field. The ability to continuously update the encyclopedia essentially means that it will retain its relevance as an easily accessible and important source of information for students, researchers, and clinicians whether they be working in academia, industry, or the hospital sectors.




A.
Actin.
Yuntao Wu.
Department of Molecular and Microbiology, National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, VA, USA.

Definition
Actin is a ubiquitous highly conserved 42-KDa globular protein in eukaryotic cells. There are three actin isoforms: alpha, beta, and gamma. The alpha actins are mainly found in muscle cells where they form thin filaments, part of the muscle contractile apparatus. The beta and gamma actins are found in most cell types and exist either as a monomeric form (G-actin) or as assembled, double helical, filamentous polymers called filamentous actin (F-actin or microfilaments). In non-muscle cells, the actin cytoskeleton provides mechanical support to cells and is a major driving force for cell motility. Actin also participates in many cellular processes such as cell division, vesicle and organelle movement, and signal transduction.



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Теги: энциклопедия по медицине :: медицина :: Hope :: Richman :: Stevenson :: СПИД